Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 3/20 | 0.38 |
| ▸ | ANPEP | P15144 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | ACP3 | P15309 | 2/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8527565 | 0.87 | ACP3 (0.38) | FDPSACP3 | |
| SCHEMBL8532197 | 0.86 | ANPEP (0.41) | FDPSLAP3ANPEPACP3ERAP1 | |
| SCHEMBL8528037 | 0.82 | SLC1A3 (0.36) | FDPS | |
| SCHEMBL413306 | 0.82 | FDPS (0.60) | FDPSSMN1; SMN2HIF1APTPN1PTPRC | |
| SCHEMBL8533532 | 0.81 | FDPS (0.51) | FDPSPTPN1 | |
| SCHEMBL8866944 | 0.80 | SLC1A3 (0.36) | PTPN1 | |
| SCHEMBL8531479 | 0.80 | CYP2C19 (0.43) | SMN1; SMN2 | |
| SCHEMBL8531881 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1A | |
| SCHEMBL8529948 | 0.77 | FDPS (0.55) | FDPSANPEPERAP1ERAP2 | |
| SCHEMBL5362392 | 0.76 | FDPS (0.53) | FDPSSMN1; SMN2HIF1APTPN1PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752999-B1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5698541-A | DISEASES OF CALCIUM METABOLISM; OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-16 | — | — | US | disclosed |
| EP-0752999-A1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026358-A1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1995-10-05 | — | — | WO | disclosed |