Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745046 | 0.89 | FDPS (0.41) | FDPSKIF11 | |
| SCHEMBL8527565 | 0.86 | ACP3 (0.38) | FDPSKIF11MMP8MMP14PPARG | |
| SCHEMBL8528147 | 0.81 | FDPS (0.46) | FDPSPTPN1 | |
| SCHEMBL8528037 | 0.76 | SLC1A3 (0.36) | FDPS | |
| SCHEMBL8528404 | 0.75 | FDPS (0.38) | FDPSKIF11PTPN5MMP8MMP14 | |
| SCHEMBL22770 | 0.72 | FOLH1 (0.44) | TSHR | |
| SCHEMBL8532197 | 0.71 | ANPEP (0.41) | FDPSKIF11 | |
| SCHEMBL8866944 | 0.71 | SLC1A3 (0.36) | TSHRPTPN1 | |
| SCHEMBL8531479 | 0.71 | CYP2C19 (0.43) | — | |
| SCHEMBL8532177 | 0.71 | FFAR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752999-B1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5698541-A | DISEASES OF CALCIUM METABOLISM; OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-16 | — | — | US | disclosed |