Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 8/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528407 | 0.79 | PTPN1 (0.41) | ACP3KIF11FDPS | |
| SCHEMBL8528014 | 0.79 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL8528275 | 0.77 | PTPN1 (0.48) | ACP3KIF11CTSGCMA1 | |
| SCHEMBL8529360 | 0.73 | FDPS (0.38) | ACP3FDPS | |
| SCHEMBL8527312 | 0.72 | ACP3 (0.34) | ACP3TDP1 | |
| SCHEMBL8527624 | 0.71 | CYP2C19 (0.38) | — | |
| SCHEMBL8531845 | 0.70 | MEN1 (0.38) | KIF11 | |
| SCHEMBL8529423 | 0.70 | KIF11 (0.38) | KIF11CA12MMP2MMP8CA14 | |
| SCHEMBL8532194 | 0.70 | FDPS (0.45) | TDP1FDPS | |
| SCHEMBL8532542 | 0.70 | ACP3 (0.33) | ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752999-B1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5698541-A | DISEASES OF CALCIUM METABOLISM; OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-16 | — | — | US | disclosed |