Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 2/20 | 0.36 |
| ▸ | PGK2 | P07205 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529423 | 0.87 | KIF11 (0.38) | PTPN1FOLH1ALDH1A1GAAKIF11 | |
| SCHEMBL8531845 | 0.87 | MEN1 (0.38) | PTPN1FOLH1CYP1A2KIF11 | |
| SCHEMBL8527227 | 0.86 | KIF11 (0.40) | PTPN1FOLH1PGK1PGK2KIF11 | |
| SCHEMBL8532194 | 0.86 | FDPS (0.45) | CYP1A2FDPS | |
| SCHEMBL8528275 | 0.85 | PTPN1 (0.48) | PTPN1KIF11ACP3 | |
| SCHEMBL8532545 | 0.83 | KIF11 (0.40) | PTPN1FOLH1KIF11 | |
| SCHEMBL8529288 | 0.83 | PTPN5 (0.43) | PTPN1GAAPTPN5 | |
| SCHEMBL8530829 | 0.83 | ALDH1A1 (0.40) | ALDH1A1GAA | |
| SCHEMBL8531385 | 0.82 | GRM4 (0.39) | PTPN1ALDH1A1KIF11 | |
| SCHEMBL8532434 | 0.82 | GRM4 (0.40) | PTPN1FOLH1KIF11PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698541-A | DISEASES OF CALCIUM METABOLISM; OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-16 | — | — | US | claimed |
| EP-0752999-B1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5698541-A | DISEASES OF CALCIUM METABOLISM; OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-16 | — | — | US | disclosed |
| EP-0752999-A1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026358-A1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1995-10-05 | — | — | WO | disclosed |