SCHEMBL8528204

SCHEMBL8528204

Oc1ccc(OC2Cc3ccccc3C2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.47
FFAR1 O14842 1/20 0.47
LTA4H P09960 1/20 0.43
NR1H2 P55055 1/20 0.43
BAX Q07812 1/20 0.43
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
GRIN1 Q05586 2/20 0.38
GRIN2B Q13224 2/20 0.38
GAA P10253 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
PTGS1 P23219 1/20 0.38
SLC6A2 P23975 1/20 0.38
CYP2C19 P33261 1/20 0.38
PTGS2 P35354 1/20 0.38
SLC6A3 Q01959 1/20 0.38
HIF1A Q16665 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8530045 0.88 IDO1 (0.44) IDO1FFAR1LTA4HNR1H2BAX
SCHEMBL1746641 0.80 SLC6A4 (0.51) IDO1FFAR1GAASLC6A2SLC6A3
SCHEMBL8528893 0.79 OPRM1 (0.49) IDO1FFAR1MEN1KMT2ALMNA
SCHEMBL19533665 0.77 SMN1; SMN2 (0.53) FFAR1KMT2AGAALMNAPDE4A
SCHEMBL20455794 0.76 MEN1 (0.48) LTA4HNR1H2BAXMEN1KMT2A
SCHEMBL16902836 0.76 MEN1 (0.48) LTA4HNR1H2BAXMEN1KMT2A
SCHEMBL4777450 0.76 IDO1 (0.47) IDO1FFAR1SLC6A2SLC6A3SLC6A4
SCHEMBL3497927 0.74 FFAR1 (0.55) FFAR1GAALMNAPTGS1ADRB2
SCHEMBL1837838 0.72 PARP10 (0.53) FFAR1MEN1KMT2AESR1ESR2
SCHEMBL10858201 0.72 PARP10 (0.58) FFAR1MEN1KMT2AESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0877730-A1 ARYL ACRYLICS FOR USE AS FUNGICIDE MONSANTO COMPANY (US) 1998-11-18 EP disclosed
US-5739140-A AGRICULTURAL FUNGICIDES MONSANTO COMPANY (US) 1998-04-14 US disclosed
WO-1997016413-A9 ARYL ACRYLICS FOR USE AS FUNGICIDE 1997-08-14 WO disclosed
WO-1997016413-A1 ARYL ACRYLICS FOR USE AS FUNGICIDE MONSANTO COMPANY (US) 1997-05-09 WO disclosed