SCHEMBL8528255

SCHEMBL8528255

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nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MME P08473 3/20 0.52
PTGS1 P23219 1/20 0.47
SLC7A11 Q9UPY5 1/20 0.47
PDCD1LG2 Q9BQ51 1/20 0.45
CD274 Q9NZQ7 1/20 0.45
ACE P12821 1/20 0.41
FNTA P49354 7/20 0.39
FNTB P49356 7/20 0.39
ENPEP Q07075 2/20 0.39
CA2 P00918 2/20 0.38
CA1 P00915 1/20 0.38
PGGT1B P53609 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8528253 1.00 MME (0.52) MMEPTGS1SLC7A11PDCD1LG2CD274
SCHEMBL11324778 1.00 MME (0.52) MMEPTGS1SLC7A11PDCD1LG2CD274
SCHEMBL11324786 1.00 MME (0.52) MMEPTGS1SLC7A11PDCD1LG2CD274
SCHEMBL29351638 0.94 MME (0.48) MMEPTGS1SLC7A11PDCD1LG2CD274
SCHEMBL29793176 0.90 MME (0.46) MMEPTGS1SLC7A11PDCD1LG2CD274
SCHEMBL30272523 0.88 OPRM1 (0.46) MMEPDCD1LG2CD274ACEFNTA
SCHEMBL30603413 0.88 OPRM1 (0.46) MMEPDCD1LG2CD274ACEFNTA
SCHEMBL30811198 0.88 MMP1 (0.44) MMEPTGS1SLC7A11PDCD1LG2CD274
SCHEMBL6791478 0.87 MME (0.51) MMEPTGS1SLC7A11ACEFNTA
SCHEMBL6791475 0.87 MME (0.51) MMEPTGS1SLC7A11ACEFNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4448545-B1 MANUFACTURING PROCESS FOR THE PRODUCTION OF LINACLOTIDE CHEMI SPA (IT) 2025-08-20 EP claimed
US-20260117070-A1 NEAR-INFRARED FLUORESCENT HEPTAMETHINE DYE CONJUGATES WITH FAVORABLE BLEACHING PROPERTIES HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM GESUNDHEIT & UMWELT GMBH (DE) 2026-04-30 US disclosed
US-12570729-B2 Antibody fragment based antifungal conjugate selectively targeting candida ABGENICS LIFESCIENCES PRIVATE LIMITED (IN) 2026-03-10 US disclosed
EP-4684030-A2 METHOD OF DEPROTECTING AT LEAST ONE D-AMINO ACID AND/OR D-AMINO ACID DERIVATIVE PROTECTED FUNCTIONAL GROUP Martin-Luther-Universität Halle-Wittenberg (DE) 2026-01-28 EP disclosed
EP-4610269-A1 UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR (UPAR) LIGANDS FOR DIAGNOSTIC OR THERAPEUTIC USE 3B Pharmaceuticals GmbH (DE) 2025-09-03 EP disclosed
CN-119015278-B Cymosine-polypeptide coupled compound, and preparation method and application thereof 广州医科大学 2025-03-14 CN disclosed
US-20250066418-A1 CYSTEINE PEPTIDE-ENABLED ANTIBODIES CITY OF HOPE 2025-02-27 US disclosed
CN-119015278-A Novel use of cytisine, cytisine-polypeptide coupled compound, preparation method and use thereof 广州医科大学 2024-11-26 CN disclosed
WO-2024227957-A2 METHOD OF DEPROTECTING AT LEAST ONE D-AMINO ACID AND/OR D-AMINO ACID DERIVATIVE PROTECTED FUNCTIONAL GROUP Martin-Luther-Universität Halle-Wittenberg (DE) 2024-11-07 WO disclosed
US-20240092878-A1 AN ANTIBODY FRAGMENT BASED ANTIFUNGAL CONJUGATE SELECTIVELY TARGETING CANDIDA ABGENICS LIFESCIENCES PRIVATE LIMITED (IN) 2024-03-21 US disclosed
CN-117701633-A Method for regulating high mannose sugar type antibody in CHO cell, CHO cell and application thereof 上海凯莱英生物技术有限公司 2024-03-15 CN disclosed
JP-2024015361-A STABLE SOLID FORMULATIONS OF GC-C RECEPTOR AGONIST POLYPEPTIDE SUITABLE FOR ORAL ADMINISTRATION アイアンウッド ファーマシューティカルズ インコーポレイテッド 2024-02-01 JP disclosed
CN-116716324-A Alkane degradation gene, protein and application thereof 山东省科学院生态研究所(山东省科学院中日友好生物技术研究中心) 2023-09-08 CN disclosed
CN-116287039-A Biological method for synthesizing spermidine by cell-free catalysis 南京工业大学 2023-06-23 CN disclosed
US-20230128688-A1 DIRECTED CONJUGATION TECHNOLOGIES KLEO PHARMACEUTICALS, INC. 2023-04-27 US disclosed
CN-113429453-B CTV tripeptide and application thereof 江西农业大学 2023-04-07 CN disclosed
CN-114478789-A anti-PD-L1 and OX40 bispecific antibodies and uses thereof 安徽安科生物工程(集团)股份有限公司 2022-05-13 CN disclosed
CN-108040482-B Composition for colon cleansing and treatment of gastrointestinal disorders 硬木药品公司 2022-03-29 CN disclosed
EP-0885899-A1 Method for obtaining peptide fragments by use of fluorinated organic acids SEIKO INSTRUMENTS INC. (JP) 1998-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570729-B2 Antibody fragment based antifungal conjugate selectively targeting candida SERPINH1, HM13, NGLY1 MME 50/4885PTGS1 4316/4885SLC7A11 1771/4885
US-20230128688-A1 DIRECTED CONJUGATION TECHNOLOGIES CD2BP2, CD2, CD47 MME 653/4885PTGS1 4806/4885SLC7A11 4036/4885
US-20250066418-A1 CYSTEINE PEPTIDE-ENABLED ANTIBODIES LNPEP, CSTB, PTMS MME 495/4885PTGS1 3581/4885SLC7A11 18/4885
US-20260117070-A1 NEAR-INFRARED FLUORESCENT HEPTAMETHINE DYE CONJUGATES WITH FAVORABLE BLEACHING PROPERTIES CBR1, CBR3, NR2E3 MME 2489/4885PTGS1 2677/4885SLC7A11 1908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.