SCHEMBL8528258

SCHEMBL8528258

CCOC(=O)C(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
ALDH1A1 P00352 5/20 0.43
ALOX15 P16050 2/20 0.43
TSHR P16473 2/20 0.43
CYP3A4 P08684 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
LMNA P02545 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
SOAT1 P35610 1/20 0.40
FDPS P14324 3/20 0.37
TRPA1 O75762 1/20 0.37
LAP3 P28838 1/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1557218 0.78 CYP2D6 (0.46) CYP2D6CYP2C9CYP2C19ALDH1A1ALOX15
SCHEMBL27725192 0.78 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4FDPS
SCHEMBL2991456 0.76 POLB (0.42) CYP2D6CYP2C9CYP2C19ALDH1A1ALOX15
SCHEMBL9468717 0.76 CYP2D6 (0.44) CYP2D6CYP2C9CYP2C19ALDH1A1ALOX15
SCHEMBL9542069 0.76 CYP2D6 (0.44) CYP2D6CYP2C9CYP2C19ALDH1A1ALOX15
SCHEMBL9067967 0.76 ALDH1A1 (0.41) CYP2D6CYP2C9CYP2C19ALDH1A1ALOX15
SCHEMBL829655 0.76 CYP2D6 (0.44) CYP2D6CYP2C9CYP2C19ALDH1A1ALOX15
SCHEMBL2351207 0.74 ALDH1A1 (0.40) CYP2D6CYP2C9CYP2C19ALDH1A1ALOX15
SCHEMBL2978555 0.73 ALDH1A1 (0.42) CYP2D6CYP2C9CYP2C19ALDH1A1ALOX15
Phosphoric Acid SCHEMBL27426833 0.73 ALDH1A1 (0.42) CYP2D6CYP2C9CYP2C19ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9694357-B1 Multi-acid polymers and methods of making the same NISSAN NORTH AMERICA, INC. (US) 2017-07-04 US claimed
US-20170274368-A1 MULTI-ACID POLYMERS AND METHODS OF MAKING THE SAME NISSAN MOTOR CO., LTD. (JP) 2017-09-28 US disclosed
US-20170279144-A1 MULTI-ACID POLYMERS FROM MULTIFUNCTIONAL AMINO ACIDS AND SULFONYL HALIDE PRECURSORS AND METHODS OF MAKING THE SAME NISSAN MOTOR CO., LTD. (JP) 2017-09-28 US disclosed
US-9694357-B1 Multi-acid polymers and methods of making the same NISSAN NORTH AMERICA, INC. (US) 2017-07-04 US disclosed
EP-0885886-A1 NOVEL PYRIDINECARBOXAMIDE DERIVATIVES Nisshin Flour Milling Co., Ltd. (JP) 1998-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170274368-A1 MULTI-ACID POLYMERS AND METHODS OF MAKING THE SAME FRS2, FXR2, PFAS CYP2D6 4154/4885CYP2C9 4322/4885CYP2C19 4481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.