SCHEMBL8528299

SCHEMBL8528299

O=C(OCl)[C@H](O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.58
MAPK1 P28482 1/20 0.58
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
HPGD P15428 1/20 0.47
KMT2A Q03164 2/20 0.45
CYP2D6 P10635 3/20 0.45
CYP2C9 P11712 1/20 0.45
HSD17B10 Q99714 1/20 0.45
CHRM2 P08172 2/20 0.44
CHRM1 P11229 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CHRM3 P20309 2/20 0.44
CHRM4 P08173 1/20 0.44
CHRM5 P08912 1/20 0.44
BLM P54132 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
SRC P12931 2/20 0.43
NR1I2 O75469 1/20 0.42
ABCB11 O95342 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29136154 1.00 LMNA (0.58) LMNAMAPK1CES2CES1HPGD
Hydrochloric Acid SCHEMBL9617551 0.98 LMNA (0.56) LMNAMAPK1CES2CES1HPGD
SCHEMBL28180749 0.98 LMNA (0.56) LMNAMAPK1CES2CES1HPGD
SCHEMBL352390 0.82 LMNA (0.62) LMNAMAPK1CES2CES1HPGD
SCHEMBL1951103 0.82 LMNA (0.62) LMNAMAPK1CES2CES1HPGD
SCHEMBL19489392 0.80 LMNA (0.60) LMNAMAPK1CES2CES1HPGD
SCHEMBL529525 0.80 L3MBTL1 (0.56) LMNAMAPK1CES2CES1KMT2A
SCHEMBL10787054 0.78 LMNA (0.58) LMNAMAPK1CES2CES1HPGD
SCHEMBL19107009 0.78 LMNA (0.58) LMNAMAPK1CES2CES1HPGD
SCHEMBL12381451 0.78 LMNA (0.58) LMNAMAPK1CES2CES1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112694488-B Synthesis method of L-type cefamandole nafate 苏州盛达药业有限公司 2022-04-22 CN claimed
CN-113354534-A Preparation method of D- (-) -formyl mandelic acid chloride 江西科苑生物股份有限公司 2021-09-07 CN claimed
CN-112694488-A Synthesis method of L-type cefamandole nafate 苏州盛达药业有限公司 2021-04-23 CN claimed
CN-110204557-A A kind of preparation method of Mandokef sodio-derivative 苏州盛达药业有限公司 2019-09-06 CN claimed
CN-106565750-B A kind of synthetic method of dextrorotation Mandokef acid 哈药集团制药总厂 2018-09-11 CN claimed
CN-108440040-A A kind of landscape flowers Nutrition Soil and preparation method thereof 合肥申沃园艺有限公司 2018-08-24 CN claimed
CN-108410831-A Ketoacid reductase, gene, engineering bacterium and application in synthesis of chiral aromatic 2-hydroxy acid 浙江工业大学 2018-08-17 CN claimed
CN-108101623-A A kind of preparation method of Flower nutrient soil 浦江县合洪园艺研发有限公司 2018-06-01 CN claimed
CN-108083934-A A kind of preparation method of nano-sized carbon compoiste fertilizer 浦江县合洪园艺研发有限公司 2018-05-29 CN claimed
CN-108083885-A For increasing fertilizer of tamato fruit hardness and preparation method thereof 兰溪市奥而特农业科技有限公司 2018-05-29 CN claimed
CN-101085781-B Method for preparing cefonicid or its medicinal salt and intermediate SHENZHEN SALUBRIS PHARM CO LTD 2010-05-26 CN claimed
CN-101134943-B Bacillus alcaligenes and method for preparing single enantiomer amygdalic acid UNIV EAST CHINA SCIENCE & TECH 2010-05-19 CN claimed
CN-101613666-A One bacillus and purposes UNIV EAST CHINA SCIENCE & TECH 2009-12-30 CN claimed
CN-101443079-A Antibacterial extracellular polysaccharide solvating system MEDTRONIC XOMED INC (US) 2009-05-27 CN claimed
CN-100463904-C Process for preparing diltiazem intermediate NINGBO ENGINEERING COLLEGE (CN) 2009-02-25 CN claimed
CN-100445375-C Modified nitrilases and their use in methods for the production of carboxylic acids BASF AG (DE) 2008-12-24 CN claimed
CN-101134943-A Bacillus alcaligenes and method for preparing single enantiomer amygdalic acid UNIV EAST CHINA SCIENCE & TECH (CN) 2008-03-05 CN claimed
CN-101085781-A Method for preparing cefonicid or its medicinal salt and intermediate SHENZHEN SALUBRIS PHARMACEUTIC (CN) 2007-12-12 CN claimed
CN-1907977-A Process for preparing diltiazem intermediate NINGBO ENGINEERING COLLEGE (CN) 2007-02-07 CN claimed
CN-1753990-A Modified nitrilases and their use in methods for the production of carboxylic acids BASF AG (DE) 2006-03-29 CN claimed