Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CES2 | O00748 | 2/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1951103 | 1.00 | LMNA (0.62) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL2687707 | 0.91 | LMNA (0.58) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL8630181 | 0.90 | LMNA (0.52) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL28860143 | 0.88 | LMNA (0.55) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL11083519 | 0.87 | LMNA (0.54) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL378836 | 0.87 | LMNA (0.54) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL2761810 | 0.87 | LMNA (0.54) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL1040186 | 0.87 | LMNA (0.54) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL9764591 | 0.86 | LMNA (0.52) | LMNAMAPK1CES2CES1HPGD | |
| Hydrochloric Acid SCHEMBL5367883 | 0.86 | LMNA (0.52) | LMNAMAPK1CES2CES1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120093737-A1 | LIGHT-ABSORBING COMPOSITIONS AND METHODS OF USE | ALLELE BIOTECHNOLOGY AND PHARMACEUTICALS, INC. | 2012-04-19 | — | — | US | disclosed |
| US-20120076842-A1 | COSMETIC USE OF TYR-ARG DIPEPTIDE TO COMBAT CUTANEOUS SAGGING | SEDERMA (FR) | 2012-03-29 | — | — | US | disclosed |
| EP-2419076-A2 | COSMETIC COMPOSITIONS COMPRISING ORIDONIN AND NEW COSMETIC USES | Sederma (FR) | 2012-02-22 | — | — | EP | disclosed |
| US-20120028916-A1 | COSMETIC COMPOSITIONS COMPRISING ORIDONIN AND NEW COSMETIC USES | SEDERMA (FR) | 2012-02-02 | — | — | US | disclosed |
| US-20120014887-A1 | NEW COMPOUNDS, IN PARTICULAR PEPTIDES, COMPOSITIONS COMPRISING THEM AND COSMETIC AND DERMO-PHARMACEUTICAL USES | SEDERMA (FR) | 2012-01-19 | — | — | US | disclosed |
| EP-2382231-A2 | NEW COMPOUNDS, IN PARTICULAR PEPTIDES, COMPOSITIONS COMPRISING THEM AND COSMETIC AND DERMOPHARMACEUTICAL USES | Sederma (FR) | 2011-11-02 | — | — | EP | disclosed |
| EP-2382230-A2 | KXK-PEPTIDE COMPOSITIONS FOR COSMETIC AND DERMO-PHARMACEUTIC USES | Sederma (FR) | 2011-11-02 | — | — | EP | disclosed |
| US-20110250276-A1 | Cosmetic Composition Containing Acetylated Oligoglucuronans | SEDERMA, S.A.S. (FR) | 2011-10-13 | — | — | US | disclosed |
| EP-2367852-A1 | COSMETIC COMPOSITION CONTAINING ACETYLATED OLIGOGLUCURONANS | Sederma (FR) | 2011-09-28 | — | — | EP | disclosed |
| EP-2046283-B1 | COMPOSITION COMPRISING SARSASAPOGENIN | SEDERMA SA (FR) | 2011-03-16 | — | — | EP | disclosed |
| US-20110045036-A1 | Cosmetic Compositions Comprising at Least One Peptide with at Least One Immobilized Aromatic Cycle | SEDERMA (FR) | 2011-02-24 | — | — | US | disclosed |
| US-20110033507-A1 | Polypeptides KXK and Their Use | SEDERMA (FR) | 2011-02-10 | — | — | US | disclosed |
| US-20110002865-A1 | MOISTURIZING COSMETIC COMPOSITION COMPRISING A COMBINATION OF HOMARINE AND ERYTHRITOL | SEDERMA, S.A.S. (FR) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120014887-A1 | NEW COMPOUNDS, IN PARTICULAR PEPTIDES, COMPOSITIONS COMPRISING THEM AND COSMETIC AND DERMO-PHARMACEUTICAL USES | CUTA, PLOD3, MC1R | LMNA 1856/4885MAPK1 1934/4885CES2 4406/4885 |
| US-20110033507-A1 | Polypeptides KXK and Their Use | NPR3, NGLY1, NPR1 | LMNA 828/4885MAPK1 3481/4885CES2 4322/4885 |
| US-20120076842-A1 | COSMETIC USE OF TYR-ARG DIPEPTIDE TO COMBAT CUTANEOUS SAGGING | ARGLU1, CUTA, ARG1 | LMNA 3387/4885MAPK1 2953/4885CES2 2466/4885 |
| US-20110045036-A1 | Cosmetic Compositions Comprising at Least One Peptide with at Least One Immobilized Aromatic Cycle | TYR, XPA, MC1R | LMNA 268/4885MAPK1 2667/4885CES2 2836/4885 |
| US-20110002865-A1 | MOISTURIZING COSMETIC COMPOSITION COMPRISING A COMBINATION OF HOMARINE AND ERYTHRITOL | AQP1, CUTA, AQP3 | LMNA 2297/4885MAPK1 3877/4885CES2 2359/4885 |
| US-20110250276-A1 | Cosmetic Composition Containing Acetylated Oligoglucuronans | GLA, OGA, CUTA | LMNA 620/4885MAPK1 1478/4885CES2 3226/4885 |
| US-20120028916-A1 | COSMETIC COMPOSITIONS COMPRISING ORIDONIN AND NEW COSMETIC USES | DPM1, MC1R, SLTM | LMNA 1393/4885MAPK1 3655/4885CES2 2268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.