Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 5/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 15/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8527025 | 0.86 | DRD3 (0.46) | DRD3DRD2SIGMAR1 | |
| SCHEMBL8526587 | 0.85 | DRD3 (0.43) | DRD3DRD2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9091460 | 0.85 | DRD3 (0.45) | DRD3DRD2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9089128 | 0.85 | DRD3 (0.43) | DRD3DRD2SIGMAR1 | |
| SCHEMBL8526354 | 0.84 | DRD2 (0.43) | DRD3DRD2 | |
| SCHEMBL8525948 | 0.78 | DRD3 (0.78) | DRD3DRD2SIGMAR1 | |
| SCHEMBL8529262 | 0.73 | SIGMAR1 (0.48) | DRD3DRD2SIGMAR1 | |
| SCHEMBL8528189 | 0.71 | SIGMAR1 (0.54) | SIGMAR1 | |
| SCHEMBL2131809 | 0.71 | KDM4E (0.59) | DRD3DRD2SIGMAR1 | |
| SCHEMBL9109340 | 0.71 | SIGMAR1 (0.50) | DRD3DRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539281-B1 | Naphthamides, process for their preparation and their application in the therapeutical field | INST NAT SANTE RECH MED (FR) | 1998-12-30 | — | — | EP | claimed |
| US-5498628-A | ANTIPSYCHOTIC, PSYCHOSTIMULATORY, ANTIAUTISTIC, ANTIDEPRESSANT AND HYPOTENSIVE AGENTS, PARKINSON'S DISEASE | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-03-12 | — | — | US | disclosed |