SCHEMBL8528459

SCHEMBL8528459

C=CC(=O)CNC(=O)CO

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL8529527 0.92 ALDH1A1 (0.38) TSHRALDH1A1MAPK1TDP1
SCHEMBL27268038 0.76 ALDH1A1 (0.34) TSHRALDH1A1MAPK1TDP1
SCHEMBL3055210 0.75 TSHR (0.59) TSHRALDH1A1MAPK1TDP1
SCHEMBL4345550 0.75
SCHEMBL27267652 0.74 ALDH1A1 (0.38) TSHRALDH1A1MAPK1TDP1
SCHEMBL8529030 0.74 SMN1; SMN2 (0.41) TSHRALDH1A1SMN1; SMN2MAPT
SCHEMBL11233471 0.73 TSHR (0.40) TSHRALDH1A1MAPK1TDP1SMN1; SMN2
SCHEMBL8743197 0.73
SCHEMBL27794294 0.72
SCHEMBL8523785 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5763546-A FREE RADICAL SOLUTION POLYMERIZATION; ADDITION POLYMERIZATION, CROSSLINKING BASF LACKE+FARBEN, AG (DE) 1998-06-09 US disclosed