SCHEMBL8529030

SCHEMBL8529030

C=CC(=O)CCCCNC(=O)CO

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.41
TSHR P16473 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ZDHHC20 Q5W0Z9 1/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40
NAAA Q02083 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CASP2 P42575 1/20 0.38
PRMT1 Q99873 1/20 0.36
MAPT P10636 1/20 0.36
EPHX2 P34913 2/20 0.36
SLC6A5 Q9Y345 1/20 0.35
ADRA1A P35348 1/20 0.34
FAAH O00519 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8531234 0.84 ZDHHC20 (0.44) TSHRZDHHC20ZDHHC2NAAAALDH1A1
SCHEMBL8743191 0.82 SMN1; SMN2 (0.42) SMN1; SMN2TSHRMEN1KMT2AZDHHC20
SCHEMBL16371856 0.80 PRMT1 (0.45) SMN1; SMN2TSHRZDHHC20ZDHHC2ALDH1A1
SCHEMBL7707699 0.78 ALDH1A1 (0.62) SMN1; SMN2MEN1KMT2ANAAAALDH1A1
SCHEMBL1156355 0.78 ALDH1A1 (0.62) SMN1; SMN2MEN1KMT2ANAAAALDH1A1
SCHEMBL8746936 0.78 ALDH1A1 (0.62) SMN1; SMN2MEN1KMT2ANAAAALDH1A1
SCHEMBL6557587 0.78 ALDH1A1 (0.50) SMN1; SMN2TSHRALDH1A1MAPTFAAH
SCHEMBL19126158 0.77 TSHR (0.40) SMN1; SMN2TSHRMEN1KMT2AZDHHC20
SCHEMBL25544332 0.75 ALDH1A1 (0.48) SMN1; SMN2MEN1KMT2ANAAAALDH1A1
SCHEMBL8743224 0.75 TSHR (0.39) SMN1; SMN2TSHRMEN1KMT2AZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5763546-A FREE RADICAL SOLUTION POLYMERIZATION; ADDITION POLYMERIZATION, CROSSLINKING BASF LACKE+FARBEN, AG (DE) 1998-06-09 US disclosed