Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528532 | 1.00 | MAOB (0.58) | MAOBRELAMAPTESR1SMN1; SMN2 | |
| SCHEMBL8527794 | 0.87 | RELA (0.51) | MAOBRELAMAPTESR1SMN1; SMN2 | |
| SCHEMBL8527792 | 0.87 | RELA (0.51) | MAOBRELAMAPTESR1SMN1; SMN2 | |
| SCHEMBL8531029 | 0.87 | LMNA (0.54) | MAOBRELAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8528699 | 0.87 | SMN1; SMN2 (0.58) | MAOBMAPTSMN1; SMN2ALDH1A1AHR | |
| SCHEMBL8528696 | 0.87 | SMN1; SMN2 (0.58) | MAOBMAPTSMN1; SMN2ALDH1A1AHR | |
| SCHEMBL8531027 | 0.87 | LMNA (0.54) | MAOBRELAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8530770 | 0.85 | TUBB1 (0.49) | RELAMAPTESR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8530773 | 0.85 | TUBB1 (0.49) | RELAMAPTESR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8532493 | 0.84 | RELA (0.49) | MAOBRELAMAPTESR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733610-B1 | Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device | CHISSO CORP (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5635108-A | A HEXYNEDIENE DERIVATIVE | CHISSO CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0733610-A1 | Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device | Chisso Corporation (JP) | 1996-09-25 | — | — | EP | disclosed |