Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528699 | 1.00 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8531027 | 0.94 | LMNA (0.54) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8531029 | 0.94 | LMNA (0.54) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8526871 | 0.89 | AHR (0.50) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8528365 | 0.89 | AHR (0.50) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8526872 | 0.89 | AHR (0.50) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8528367 | 0.89 | AHR (0.50) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8528871 | 0.88 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8528873 | 0.88 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8528533 | 0.87 | MAOB (0.58) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733610-B1 | Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device | CHISSO CORP (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5635108-A | A HEXYNEDIENE DERIVATIVE | CHISSO CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0733610-A1 | Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device | Chisso Corporation (JP) | 1996-09-25 | — | — | EP | disclosed |