Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL507379 | 0.73 | SMN1; SMN2 (0.51) | SMN1; SMN2GAALMNAL3MBTL1CYP17A1 | |
| SCHEMBL13577115 | 0.73 | BACE1 (0.43) | BACE1LMNAALDH1A1 | |
| SCHEMBL8528756 | 0.72 | BACE1 (0.40) | BACE1LMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL7792091 | 0.72 | CNR2 (0.40) | SMN1; SMN2GAABACE1LMNAL3MBTL1 | |
| SCHEMBL7797998 | 0.72 | CNR2 (0.42) | SMN1; SMN2GAABACE1LMNAL3MBTL1 | |
| SCHEMBL5146700 | 0.72 | BACE1 (0.35) | BACE1 | |
| SCHEMBL23748259 | 0.71 | SMN1; SMN2 (0.44) | SMN1; SMN2GAALMNAL3MBTL1CYP17A1 | |
| SCHEMBL29425358 | 0.71 | LOXL2 (0.47) | BACE1 | |
| SCHEMBL15899306 | 0.71 | BACE1 (0.34) | BACE1MAPT | |
| SCHEMBL8480203 | 0.71 | ALK (0.33) | BACE1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849922-A | Preparation of substituted alkenoic acids | ELI LILLY AND COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5849766-A | Carbamoyl substituted heterocycles | ELI LILLY AND COMPANY (US) | 1998-12-15 | — | — | US | disclosed |