Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL8528937

CCCOC(C)(C)C.CCOCC.OCCO.OCCOCCO

nearest known ligand 0.50

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Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
TSHR P16473 2/20 0.45
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
THRB P10828 1/20 0.41
HTT P42858 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.40
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(Hydroxyethyl)Ether SCHEMBL4838775 0.92 TSHR (0.52) ALDH1A1TSHRMEN1KMT2ATHRB
Ether SCHEMBL2878645 0.85 ALDH1A1 (0.55) ALDH1A1TSHRMEN1KMT2ATHRB
Ethylene Glycol SCHEMBL8858006 0.85 TSHR (0.35) ALDH1A1TSHRMEN1KMT2ATHRB
Di(Hydroxyethyl)Ether SCHEMBL8586098 0.85 MEN1 (0.57) ALDH1A1TSHRMEN1KMT2ATHRB
SCHEMBL8528943 0.83 MEN1 (0.48) ALDH1A1TSHRMEN1KMT2ATHRB
Di(Hydroxyethyl)Ether SCHEMBL6692088 0.83 ALDH1A1 (0.65) ALDH1A1TSHRMEN1KMT2ATHRB
Di(Hydroxyethyl)Ether SCHEMBL20398410 0.81 ALDH1A1 (0.56) ALDH1A1TSHRMEN1KMT2ATHRB
Di(Hydroxyethyl)Ether SCHEMBL4137670 0.81 ALDH1A1 (0.55) ALDH1A1TSHRMEN1KMT2ATHRB
Propanol SCHEMBL11142726 0.80 TSHR (0.35) ALDH1A1TSHRMEN1KMT2ATHRB
Di(Hydroxyethyl)Ether SCHEMBL21633769 0.80 ALDH1A1 (0.77) ALDH1A1TSHRMEN1KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0886718-A1 OIL AND GAS FIELD CHEMICALS BP Chemicals Limited (GB) 1998-12-30 EP claimed
WO-1997035095-A1 OIL AND GAS FIELD CHEMICALS BP CHEMICALS LIMITED (GB) 1997-09-25 WO claimed