Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305205 | 0.91 | CYP1A2 (0.61) | MEN1KMT2ALTA4HCYP1A2CYP2D6 | |
| SCHEMBL217345 | 0.83 | MEN1 (0.62) | MEN1KMT2ALTA4HCYP1A2CYP2D6 | |
| SCHEMBL631023 | 0.81 | ALDH1A1 (0.66) | MEN1KMT2ALTA4HCYP1A2CYP2D6 | |
| SCHEMBL55886 | 0.80 | SLC6A2 (0.48) | CYP1A2CYP2D6CYP2C19SLC6A4CYP3A4 | |
| SCHEMBL11579350 | 0.80 | LDHA (0.58) | MEN1KMT2ALTA4HCYP1A2CYP2D6 | |
| SCHEMBL4603241 | 0.80 | MEN1 (0.59) | MEN1KMT2ALTA4HCYP1A2CYP2D6 | |
| SCHEMBL4603238 | 0.80 | MEN1 (0.59) | MEN1KMT2ALTA4HCYP1A2CYP2D6 | |
| SCHEMBL9771325 | 0.79 | MEN1 (0.54) | MEN1KMT2ALTA4HCYP1A2CYP2D6 | |
| SCHEMBL9232177 | 0.79 | MEN1 (0.54) | MEN1KMT2ALTA4HCYP1A2CYP2D6 | |
| SCHEMBL1127532 | 0.79 | MEN1 (0.54) | MEN1KMT2ALTA4HCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885236-A1 | OLIGONUCLEOTIDE ANALOGS | Codon Pharmaceuticals, Inc. (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997027206-A1 | OLIGONUCLEOTIDE ANALOGS | CODON PHARMACEUTICALS, INC. (US) | 1997-07-31 | — | — | WO | disclosed |