Sugi Predict

Sugi Predict / Compounds / SCHEMBL631023

SCHEMBL631023

SCHEMBL631023

COc1ccc(CC(Cc2ccc(OC)cc2)c2ccccc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.66
▸ LTA4H P09960 1/20 0.57
▸ MEN1 O00255 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ CYP1A2 P05177 1/20 0.55
▸ CYP2D6 P10635 1/20 0.55
▸ CYP2C19 P33261 1/20 0.55
▸ LDHA P00338 1/20 0.55
▸ SLC6A4 P31645 1/20 0.53
▸ PPARG P37231 1/20 0.50
▸ PPARA Q07869 1/20 0.50
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ TDP1 Q9NUW8 1/20 0.49
▸ SIGMAR1 Q99720 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2086374 0.90 ALDH1A1 (0.68) ALDH1A1LTA4HMEN1KMT2ACYP1A2
SCHEMBL217345 0.86 MEN1 (0.62) ALDH1A1LTA4HMEN1KMT2ACYP1A2
SCHEMBL6176524 0.85 PKM (0.60) ALDH1A1LDHAPPARGPPARAL3MBTL1
SCHEMBL9856612 0.84 ALDH1A1 (0.61) ALDH1A1LTA4HMEN1KMT2ACYP1A2
SCHEMBL9857039 0.84 ALDH1A1 (0.61) ALDH1A1LTA4HMEN1KMT2ACYP1A2
SCHEMBL11579350 0.83 LDHA (0.58) ALDH1A1LTA4HMEN1KMT2ACYP1A2
SCHEMBL4603241 0.83 MEN1 (0.59) ALDH1A1LTA4HMEN1KMT2ACYP1A2
SCHEMBL4603238 0.83 MEN1 (0.59) ALDH1A1LTA4HMEN1KMT2ACYP1A2
SCHEMBL8529164 0.81 MEN1 (0.54) ALDH1A1LTA4HMEN1KMT2ACYP1A2
SCHEMBL9771325 0.81 MEN1 (0.54) ALDH1A1LTA4HMEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220380845-A1 Asymmetric Rhodamine Dye and Use Thereof in Biological Assays Life Technologies Corporation 2022-12-01 — — US disclosed
US-20220056041-A1 Modified Rhodamine Dye and use Thereof in Biological Assays Life Technologies Corporation 2022-02-24 — — US disclosed
EP-3898841-A1 ASYMMETRIC RHODAMINE DYE AND USE THEREOF IN BIOLOGICAL ASSAYS Life Technologies Corporation (US) 2021-10-27 — — EP disclosed
EP-3898842-A1 MODIFIED RHODAMINE DYE AND USE THEREOF IN BIOLOGICAL ASSAYS Life Technologies Corporation (US) 2021-10-27 — — EP disclosed
US-20210324198-A1 SILICON-SUBSTITUTED RHODAMINE DYES AND DYE CONJUGATES Life Technologies Corporation 2021-10-21 — — US disclosed
WO-2020132607-A9 ASYMMETRIC RHODAMINE DYE AND USE THEREOF IN BIOLOGICAL ASSAYS Life Technologies Corporation (US) 2020-11-26 — — WO disclosed
WO-2020132607-A1 ASYMMETRIC RHODAMINE DYE AND USE THEREOF IN BIOLOGICAL ASSAYS Life Technologies Corporation (US) 2020-06-25 — — WO disclosed
WO-2020132487-A1 MODIFIED RHODAMINE DYE AND USE THEREOF IN BIOLOGICAL ASSAYS Life Technologies Corporation (US) 2020-06-25 — — WO disclosed
US-9783560-B2 Reagents useful for synthesizing rhodamine-labeled oligonucleotides APPLIED BIOSYSTEMS, LLC (US) 2017-10-10 — — US disclosed
US-20150232494-A1 REAGENTS USEFUL FOR SYNTHESIZING RHODAMINE-LABELED OLIGONUCLEOTIDES APPLERA CORPORATION 2015-08-20 — — US disclosed
US-5552471-A Solid support reagents for the synthesis of 3'-Nitrogen containing polynucleotides THE PERKIN-ELMER CORPORATION (US) 1996-09-03 — — US disclosed
EP-0723973-A1 Nucleoside phosphorothioate derivatives, synthesis and use thereof KING'S COLLEGE LONDON (GB) 1996-07-31 — — EP disclosed
EP-0648221-A4 TRITYL MONITOR FOR AUTOMATED POLYNUCLEOTIDE SYNTHESIS. APPLIED BIOSYSTEMS (US) 1996-04-24 — — EP disclosed
WO-1996005215-A1 SOLID SUPPORT REAGENTS FOR THE SYNTHESIS OF 3'-NITROGEN CONTAINING POLYNUCLEOTIDES THE PERKIN ELMER CORPORATION (US) 1996-02-22 — — WO disclosed
EP-0648221-A1 TRITYL MONITOR FOR AUTOMATED POLYNUCLEOTIDE SYNTHESIS THE PERKIN-ELMER CORPORATION (US) 1995-04-19 — — EP disclosed
EP-0595839-A4 — — 1994-08-03 — — EP disclosed
EP-0595839-A1 METHOD AND COMPOUNDS FOR RNA SYNTHESIS THE PERKIN-ELMER CORPORATION (US) 1994-05-11 — — EP disclosed
WO-1994000471-A1 TRITYL MONITOR FOR AUTOMATED POLYNUCLEOTIDE SYNTHESIS APPLIED BIOSYSTEMS, INC. (US) 1994-01-06 — — WO disclosed
WO-1993001204-A1 METHOD AND COMPOUNDS FOR RNA SYNTHESIS APPLIED BIOSYSTEMS, INC. (US) 1993-01-21 — — WO disclosed
US-4973679-A Process for oligonucleo tide synthesis using phosphormidite intermediates UNIVERSITY PATENTS, INC. (US) 1990-11-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210324198-A1 SILICON-SUBSTITUTED RHODAMINE DYES AND DYE CONJUGATES SRI, SI, IK ALDH1A1 1849/4885LTA4H 4036/4885MEN1 1689/4885
US-20220056041-A1 Modified Rhodamine Dye and use Thereof in Biological Assays QTRT1, MRPL21, RRP1B ALDH1A1 1889/4885LTA4H 1736/4885MEN1 3054/4885
US-20150232494-A1 REAGENTS USEFUL FOR SYNTHESIZING RHODAMINE-LABELED OLIGONUCLEOTIDES RTCB, RRM2B, SNRPE ALDH1A1 2789/4885LTA4H 3569/4885MEN1 3967/4885
US-20220380845-A1 Asymmetric Rhodamine Dye and Use Thereof in Biological Assays HNRNPR, RNASEH1, HNRNPH3 ALDH1A1 2012/4885LTA4H 1901/4885MEN1 3437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.