Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848982 | 0.92 | GRIN1 (0.42) | GRIN1GRIN2BMEN1ALDH1A1CYP3A4 | |
| SCHEMBL8531551 | 0.90 | GRIN1 (0.39) | GRIN1GRIN2BMEN1ALDH1A1CYP3A4 | |
| SCHEMBL8338402 | 0.89 | — | — | |
| SCHEMBL7070555 | 0.82 | GRIN1 (0.35) | GRIN1GRIN2BMEN1ALDH1A1CYP3A4 | |
| SCHEMBL9009378 | 0.79 | NOTUM (0.30) | — | |
| SCHEMBL7848879 | 0.79 | TYMS (0.35) | — | |
| SCHEMBL7843371 | 0.78 | ALDH1A1 (0.41) | MEN1ALDH1A1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL8335901 | 0.78 | — | — | |
| SCHEMBL8530296 | 0.77 | GRIN1 (0.35) | GRIN1GRIN2BMEN1ALDH1A1CYP3A4 | |
| SCHEMBL8530286 | 0.76 | GRIN1 (0.34) | GRIN1GRIN2BMEN1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827498-A1 | NEW ANTIVIRAL SUBSTITUTED PYRIMIDINEDIONE HOMOCARBOCYCLIC NUCLEOSIDE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENTS | Samjin Pharmaceutical Co., Ltd. (KR) | 1998-03-11 | — | — | EP | disclosed |
| WO-1997030979-A1 | NEW ANTIVIRAL SUBSTITUTED PYRIMIDINEDIONE HOMOCARBOCYCLIC NUCLEOSIDE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENTS | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1997-08-28 | — | — | WO | disclosed |