SCHEMBL7848879

SCHEMBL7848879

Cc1cc(C)cc(Sc2[nH]c(=O)n(Cc3cc(Br)cc(Br)c3)c(=O)c2C(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.35
DDR1 Q08345 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7849648 0.87 GRIN1 (0.36)
SCHEMBL7843371 0.86 ALDH1A1 (0.41)
SCHEMBL7845270 0.85 MTNR1A (0.38)
SCHEMBL7846744 0.84 DDR1 (0.33) DDR1
SCHEMBL6086367 0.82 TYMS (0.37) TYMS
SCHEMBL7837651 0.80 MTNR1A (0.50)
SCHEMBL7848982 0.80 GRIN1 (0.42)
SCHEMBL7848132 0.79 GRIN1 (0.40)
SCHEMBL8529240 0.79 GRIN1 (0.35)
SCHEMBL9009378 0.78 NOTUM (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1100786-A1 ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF Samjin Pharmaceutical Co., Ltd. (KR) 2001-05-23 EP disclosed
WO-2000061564-A1 ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF SAMJIN PHARMACEUTICAL CO., LTD. (KR) 2000-10-19 WO disclosed