Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529323 | 1.00 | ATM (0.30) | ATM | |
| SCHEMBL8843122 | 1.00 | ATM (0.30) | ATM | |
| SCHEMBL15715857 | 0.80 | — | — | |
| SCHEMBL5068787 | 0.80 | ATM (0.50) | ATM | |
| SCHEMBL5065994 | 0.80 | ATM (0.50) | ATM | |
| SCHEMBL6002159 | 0.80 | ATM (0.50) | ATM | |
| SCHEMBL2498387 | 0.80 | ATM (0.50) | ATM | |
| SCHEMBL20973270 | 0.80 | ATM (0.50) | ATM | |
| SCHEMBL25364067 | 0.79 | ATM (0.42) | ATM | |
| SCHEMBL6002006 | 0.79 | DPP4 (0.34) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415365-B | Carbapenem compounds | 幽兰医药有限公司 | 2022-08-09 | — | — | CN | disclosed |
| US-20200339582-A1 | Atypical Carbapenem Antibiotics with Improved Activity Against Carbapenemase-Producing Acinetobacter baumannii | BUYNAK JOHN (US) | 2020-10-29 | — | — | US | disclosed |
| US-8841444-B2 | Process for the preparation of carbapenem compounds | RANBAXY LABORATORIES LIMITED (IN) | 2014-09-23 | — | — | US | disclosed |
| EP-1926732-B1 | A PROCESS FOR THE PREPARATION OF CARBAPENEM COMPOUNDS | RANBAXY LAB LTD (IN) | 2013-11-06 | — | — | EP | disclosed |
| WO-2012160576-A2 | A PROCESS FOR PREPARATION OF MEROPENEM | SEQUENT ANTI BIOTICS PRIVATE LIMITED (IN) | 2012-11-29 | — | — | WO | disclosed |
| EP-2326648-B1 | PROCESS FOR THE PREPARATION OF CARBAPENEM COMPOUNDS | RANBAXY LAB LTD (IN) | 2012-09-19 | — | — | EP | disclosed |
| WO-2010013223-A1 | PROCESS FOR THE PREPARATION OF CARBAPENEM COMPOUNDS | RANBAXY LABORATORIES LIMITED (IN) | 2010-02-04 | — | — | WO | disclosed |
| US-20090299057-A1 | MEROPENEM INTERMEDIATE IN NOVEL CRYSTALLINE FORM AND A METHOD OF MANUFACTURE OF MEROPENEM | KHEMKA ASHWIN A | 2009-12-03 | — | — | US | disclosed |
| EP-1926732-A2 | A PROCESS FOR THE PREPARATION OF CARBAPENEM COMPOUNDS | RANBAXY LABORATORIES, LTD. (IN) | 2008-06-04 | — | — | EP | disclosed |
| US-20070197781-A1 | PROCESSES FOR THE PREPARATION OF CARBAPENEMS | RANBAXY LABORATORIES LIMITED (IN) | 2007-08-23 | — | — | US | disclosed |
| WO-2007029084-A2 | A PROCESS FOR THE PREPARATION OF CARBAPENEM COMPOUNDS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |
| US-5700930-A | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1997-12-23 | — | — | US | disclosed |
| US-5656753-A | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1997-08-12 | — | — | US | disclosed |
| US-5371215-A | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090299057-A1 | MEROPENEM INTERMEDIATE IN NOVEL CRYSTALLINE FORM AND A METHOD OF MANUFACTURE OF MEROPENEM | NT5C3B, CYP4B1, GNE | ATM 4232/4885 |
| US-20070197781-A1 | PROCESSES FOR THE PREPARATION OF CARBAPENEMS | MGAM, SI, TREH | ATM 3078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.