SCHEMBL8529372

SCHEMBL8529372

C=Cc1ccc(OC2CCCOC2=O)cc1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
KDM4E B2RXH2 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
DYRK1A Q13627 2/20 0.34
DYRK1B Q9Y463 2/20 0.34
CLK1 P49759 1/20 0.34
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.32
MAOA P21397 1/20 0.32
PTPN1 P18031 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9963794 0.91 ALDH1A1 (0.43) ALDH1A1KDM4ESMN1; SMN2HPGDHSD17B10
SCHEMBL13131165 0.80 KDM4E (0.34) ALDH1A1KDM4ESMN1; SMN2HSD17B10MAOA
SCHEMBL13131086 0.79 SMN1; SMN2 (0.33) ALDH1A1KDM4ESMN1; SMN2HSD17B10MAOA
SCHEMBL1899432 0.78 POLB (0.54) ALDH1A1KDM4ESMN1; SMN2HPGD
SCHEMBL31708207 0.77 ALDH1A1 (0.54) ALDH1A1KDM4ESMN1; SMN2
SCHEMBL13131084 0.75 DDB1 (0.36) ALDH1A1KDM4ESMN1; SMN2HPGDHSD17B10
SCHEMBL13131055 0.74 DDB1 (0.35) ALDH1A1KDM4ESMN1; SMN2HPGDHSD17B10
SCHEMBL13130985 0.74 DDB1 (0.35) ALDH1A1KDM4ESMN1; SMN2HPGDHSD17B10
SCHEMBL13131114 0.74 EPHX2 (0.34) ALDH1A1KDM4ESMN1; SMN2HPGDHSD17B10
SCHEMBL13130993 0.73 EPHX2 (0.33) ALDH1A1KDM4ESMN1; SMN2HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0520642-B1 Resist material and pattern formation process WAKO PURE CHEM IND LTD (JP) 1998-10-28 EP disclosed
US-5670299-A COATING A PHOTORESISTS POLYMER ON A SUBSTRATE, DEVELOPMENT AND HEAT TREATMENT WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1997-09-23 US disclosed
US-5468589-A Heat resistant, photosensitive patterns WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1995-11-21 US disclosed
EP-0520642-A1 Resist material and pattern formation process WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1992-12-30 EP disclosed