Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RHEB | Q15382 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965790 | 0.81 | GAA (0.42) | ALDH1A1KCNJ1LMNAMAPT | |
| SCHEMBL19279017 | 0.80 | ALDH1A1 (0.37) | ALDH1A1MAPT | |
| SCHEMBL11431904 | 0.78 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL27876029 | 0.77 | LMNA (0.31) | LMNA | |
| SCHEMBL27629659 | 0.77 | LMNA (0.31) | LMNA | |
| SCHEMBL27876069 | 0.77 | LMNA (0.31) | LMNA | |
| SCHEMBL11432285 | 0.77 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL4724991 | 0.76 | CAPN1 (0.36) | PKMALDH1A1KCNJ1LMNAMAPT | |
| SCHEMBL27610452 | 0.75 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL28060818 | 0.75 | KDM4E (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780653-A | Nitrophenyl, 10-deacetylated substituted taxol derivatives as dual functional cytotoxic/radiosensitizers | VIVORX PHARMACEUTICALS, INC. (US) | 1998-07-14 | — | — | US | disclosed |
| WO-1996040091-A1 | DUAL FUNCTIONAL CYTOTOXIC/RADIOSENSITIZER COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | VIVORX PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |