SCHEMBL28060818

SCHEMBL28060818

C=C(C)CCc1nc([N+](=O)[O-])c[nH]1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4724991 0.80 CAPN1 (0.36) ALDH1A1
SCHEMBL8529384 0.75 PKM (0.34) ALDH1A1
SCHEMBL3965790 0.75 GAA (0.42) KDM4EALDH1A1
SCHEMBL5612633 0.75 GPR84 (0.39) KDM4EALDH1A1
SCHEMBL19279017 0.71 ALDH1A1 (0.37) KDM4EALDH1A1
SCHEMBL30721382 0.71 HRH1 (0.39) ALDH1A1
SCHEMBL29705870 0.71 ALDH1A1 (0.36) ALDH1A1
SCHEMBL11431904 0.69 ALDH1A1 (0.31) ALDH1A1
Hydrochloric Acid SCHEMBL30158596 0.69 ALDH1A1 (0.35) ALDH1A1
SCHEMBL27859428 0.69 KCNA4 (0.30) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102741259-B Nitroimidazooxazine and nitroimidazooxazole analogues and uses thereof GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (US) 2016-04-13 CN disclosed