Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529465 | 0.82 | MEN1 (0.33) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL28000563 | 0.72 | — | — | |
| SCHEMBL9627288 | 0.71 | GABRA5 (0.43) | HTTMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL8528544 | 0.61 | MEN1 (0.30) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL8528540 | 0.61 | MEN1 (0.30) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL27694286 | 0.60 | KMT2A (0.35) | TSHRHPGDHTTMEN1NPC1 | |
| SCHEMBL7079216 | 0.59 | MAPT (0.43) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL7079213 | 0.59 | MAPT (0.43) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL10516373 | 0.59 | MAPT (0.40) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL9477998 | 0.59 | MAPT (0.40) | MEN1NPC1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620228-B1 | Novel reactive thiophosphate derivatives of thia(dia)zole acetic acid and process for preparing the same | LUCKY LTD (KR) | 1998-03-11 | — | — | EP | claimed |