Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529520 | 0.82 | TSHR (0.35) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL11043855 | 0.69 | SMN1; SMN2 (0.37) | MEN1KMT2AMAPK1ALDH1A1NPC1 | |
| SCHEMBL8529459 | 0.69 | ROCK2 (0.32) | — | |
| SCHEMBL8529453 | 0.69 | ROCK2 (0.32) | — | |
| SCHEMBL10656132 | 0.68 | KMT2A (0.36) | MEN1KMT2AMAPK1ALDH1A1NPC1 | |
| SCHEMBL9462958 | 0.66 | MAPT (0.41) | MEN1KMT2AMAPK1NPC1POLB | |
| SCHEMBL9234341 | 0.66 | MAPT (0.41) | MEN1KMT2AMAPK1NPC1POLB | |
| SCHEMBL10743055 | 0.66 | MAPT (0.39) | MEN1KMT2AMAPK1ALDH1A1NPC1 | |
| SCHEMBL11067512 | 0.66 | MAPT (0.39) | MEN1KMT2AMAPK1ALDH1A1NPC1 | |
| SCHEMBL11067530 | 0.66 | MAPT (0.39) | MEN1KMT2AMAPK1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620228-B1 | Novel reactive thiophosphate derivatives of thia(dia)zole acetic acid and process for preparing the same | LUCKY LTD (KR) | 1998-03-11 | — | — | EP | claimed |