Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6791297 | 0.80 | GABRA5 (0.47) | GABRA5GABRB2HSD17B10MAPTALDH1A1 | |
| SCHEMBL10991421 | 0.74 | GABRA5 (0.58) | GABRA5GABRB2HSD17B10MAPTALDH1A1 | |
| SCHEMBL8768623 | 0.71 | GABRA5 (0.43) | GABRA5GABRB2HSD17B10MAPTALDH1A1 | |
| SCHEMBL8526129 | 0.71 | GABRA5 (0.43) | GABRA5GABRB2HSD17B10MAPTALDH1A1 | |
| SCHEMBL8529520 | 0.71 | TSHR (0.35) | MAPTALDH1A1NPC1RAB9AHTT | |
| SCHEMBL3999942 | 0.69 | GABRA5 (0.51) | GABRA5GABRB2HSD17B10MAPTALDH1A1 | |
| SCHEMBL2789164 | 0.69 | GABRA5 (0.51) | GABRA5GABRB2HSD17B10MAPTALDH1A1 | |
| SCHEMBL7079213 | 0.69 | MAPT (0.43) | HSD17B10MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL7079216 | 0.69 | MAPT (0.43) | HSD17B10MAPTALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8913011 | 0.68 | GABRA5 (0.50) | GABRA5GABRB2HSD17B10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091382-A | CEPHALOSPORIN DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |