Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.39 |
| ▸ | IKBKB | O14920 | 2/20 | 0.37 |
| ▸ | CHUK | O15111 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532246 | 0.90 | SLC9A1 (0.43) | SLC9A1 | |
| SCHEMBL8610375 | 0.84 | PTGS2 (0.39) | IKBKBCHUKPTGS1PTGS2 | |
| SCHEMBL8533389 | 0.76 | SLC9A1 (0.38) | SLC9A1IKBKBCHUKHTR2B | |
| SCHEMBL27369644 | 0.75 | PTGS2 (0.36) | IKBKBCHUKPTGS2 | |
| SCHEMBL8610258 | 0.72 | PTGS2 (0.39) | IKBKBCHUKPTGS2 | |
| SCHEMBL8533060 | 0.69 | SLC9A1 (0.40) | SLC9A1IKBKBCHUKHTR2B | |
| SCHEMBL8528444 | 0.69 | SLC9A1 (0.50) | SLC9A1 | |
| SCHEMBL8533224 | 0.67 | SLC9A1 (0.49) | SLC9A1PTGS1PTGS2 | |
| SCHEMBL8533404 | 0.67 | HTR2B (0.39) | SLC9A1IKBKBCHUKHTR2B | |
| SCHEMBL8533081 | 0.67 | SLC9A1 (0.40) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699660-B1 | Arylbenzoylguanidines | MERCK PATENT GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5807896-A | Arylbenzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTING (DE) | 1998-09-15 | — | — | US | disclosed |
| EP-0699660-A2 | Arylbenzoylguanidines | MERCK PATENT GmbH (DE) | 1996-03-06 | — | — | EP | disclosed |