Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534496 | 0.91 | SLC9A1 (0.55) | SLC9A1 | |
| SCHEMBL8533064 | 0.84 | PTGS1 (0.40) | PTGS1PTGS2 | |
| SCHEMBL8533826 | 0.83 | SLC9A1 (0.43) | SLC9A1 | |
| SCHEMBL8533081 | 0.79 | SLC9A1 (0.40) | SLC9A1 | |
| SCHEMBL8531444 | 0.76 | SLC9A1 (0.60) | SLC9A1 | |
| SCHEMBL8533097 | 0.73 | PTGS2 (0.38) | SLC9A1PTGS2 | |
| SCHEMBL8533060 | 0.72 | SLC9A1 (0.40) | SLC9A1 | |
| SCHEMBL8533960 | 0.71 | SLC9A1 (0.73) | SLC9A1 | |
| SCHEMBL8532048 | 0.71 | SLC9A1 (0.43) | SLC9A1 | |
| SCHEMBL8532555 | 0.71 | SLC9A1 (0.81) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699660-B1 | Arylbenzoylguanidines | MERCK PATENT GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5807896-A | Arylbenzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTING (DE) | 1998-09-15 | — | — | US | disclosed |
| EP-0699660-A2 | Arylbenzoylguanidines | MERCK PATENT GmbH (DE) | 1996-03-06 | — | — | EP | disclosed |