SCHEMBL852957

SCHEMBL852957

CCOC(=O)c1ccc(CCl)o1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.58
GAA P10253 1/20 0.58
KDM4E B2RXH2 5/20 0.57
MAPT P10636 4/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
POLB P06746 2/20 0.57
TLR2 O60603 1/20 0.57
NSD2 O96028 1/20 0.57
PKM P14618 1/20 0.57
MPI P34949 1/20 0.57
GRK6 P43250 1/20 0.57
RECQL P46063 1/20 0.57
TLR1 Q15399 1/20 0.57
TLR6 Q9Y2C9 1/20 0.57
HDAC4 P56524 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
LMNA P02545 3/20 0.55
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
TSHR P16473 5/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL15823986 0.98 ALDH1A1 (0.57) ALDH1A1GAAKDM4EMAPTL3MBTL1
SCHEMBL151035 0.86 ALDH1A1 (0.60) ALDH1A1GAAKDM4EMAPTL3MBTL1
SCHEMBL6240522 0.84 ALDH1A1 (0.59) ALDH1A1GAAKDM4EMAPTL3MBTL1
SCHEMBL2093655 0.84 ALDH1A1 (0.58) ALDH1A1GAAKDM4EMAPTL3MBTL1
SCHEMBL4677058 0.84 TSHR (0.50) ALDH1A1GAAKDM4EMAPTL3MBTL1
SCHEMBL449698 0.83 HDAC4 (0.73) ALDH1A1GAAKDM4EMAPTL3MBTL1
SCHEMBL6445905 0.83 HDAC4 (0.59) ALDH1A1GAAKDM4EMAPTL3MBTL1
SCHEMBL2181967 0.83 ALDH1A1 (0.57) ALDH1A1GAAKDM4EMAPTL3MBTL1
SCHEMBL13064782 0.83 ALDH1A1 (0.60) ALDH1A1GAAKDM4EMAPTL3MBTL1
SCHEMBL853606 0.83 ALDH1A1 (0.57) ALDH1A1GAAKDM4EMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 478 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930868-A Catalyst component containing furoic acid ester compound, preparation method thereof, olefin polymerization catalyst, olefin polymerization method and olefin polymer 中国石油化工股份有限公司 2025-05-06 CN claimed
CN-109966507-A PH and the macromolecular nano-prodrug of redox double-response of a kind of cancer target and the preparation method and application thereof 广州医科大学 2019-07-05 CN claimed
US-12522618-B2 Copper complexes for treatment of neurodegenerative disorders ALS THERAPY DEVELOPMENT INSTITUTE (US) 2026-01-13 US disclosed
EP-4650345-A1 HETEROCYCLIC COMPOUND AND USE THEREOF IN MEDICINE Kangbaida (Sichuan) Biotechnology Co., Ltd. (CN) 2025-11-19 EP disclosed
US-12459929-B2 GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods for their use CARMOT THERAPEUTICS INC. (US) 2025-11-04 US disclosed
EP-4563199-A2 GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE Carmot Therapeutics, Inc. (US) 2025-06-04 EP disclosed
EP-4558494-A1 1,3,4-OXADIAZOLE DERIVATIVES AS SELECTIVE HISTONE DEACETYLASE 6 INHIBITORS ITALFARMACO S.p.A. (IT) 2025-05-28 EP disclosed
US-20250154137-A1 GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE CARMOT THERAPEUTICS, INC. 2025-05-15 US disclosed
CN-119930868-A Catalyst component containing furoic acid ester compound, preparation method thereof, olefin polymerization catalyst, olefin polymerization method and olefin polymer 中国石油化工股份有限公司 2025-05-06 CN disclosed
CN-119390668-A Compound with ketoxime ether structure and application thereof 复旦大学 2025-02-07 CN disclosed
US-20240368195-A1 COPPER COMPLEXES FOR TREATMENT OF NEURODEGENERATIVE DISORDERS ALS THERAPY DEVELOPMENT INST (US) 2024-11-07 US disclosed
US-5075301-A FURAN DERIVATIVES USEFUL FOR THE TREATMENT OF GASTRO-INTESTINAL DISORDERS KYOWA HAKKO KOGYO, CO., LTD. (JP) 1991-12-24 US disclosed
US-5001138-A Insecticides NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) 1991-03-19 US disclosed
EP-0413343-A2 Furan derivatives KYOWA HAKKO KOGYO CO., LTD. (JP) 1991-02-20 EP disclosed
EP-0393738-A1 Hydroxyalkylfuranyl derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1990-10-24 EP disclosed
US-4845106-A INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-07-04 US disclosed
US-4742060-A 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) 1988-05-03 US disclosed
EP-0192060-A1 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1986-08-27 EP disclosed
US-4282246-A Antidiabetic furancarboxylic and thiphenecarboxylic acids PFIZER INC. (US) 1981-08-04 US disclosed
US-4195023-A ELASTASE INHIBITORS, TREATMENT OF EMPHYSEMA MERCK & CO., INC. (US) 1980-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250154137-A1 GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE GLP1R, GCGR, GIPR ALDH1A1 3497/4885GAA 2211/4885KDM4E 3526/4885
US-12459929-B2 GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods for their use GLP1R, GCGR, GIPR ALDH1A1 3497/4885GAA 2211/4885KDM4E 3526/4885
US-20240368195-A1 COPPER COMPLEXES FOR TREATMENT OF NEURODEGENERATIVE DISORDERS SOD1, SMN1; SMN2, CLN6 ALDH1A1 1721/4885GAA 50/4885KDM4E 3459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.