Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.43 |
| ▸ | AGT | P01019 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533668 | 0.87 | AGTR1 (0.45) | AGTR1AGTAGTR2 | |
| SCHEMBL8602921 | 0.83 | AGTR1 (0.43) | AGTR1AGTAGTR2ADORA3ADORA2A | |
| SCHEMBL9296555 | 0.77 | AGTR1 (0.54) | AGTR1AGTAGTR2 | |
| SCHEMBL8529152 | 0.72 | AGT (0.42) | AGTR1AGTAGTR2 | |
| SCHEMBL8532658 | 0.72 | AGT (0.43) | AGTR1AGTAGTR2 | |
| SCHEMBL8600996 | 0.72 | AGT (0.42) | AGTR1AGTAGTR2 | |
| SCHEMBL9591726 | 0.72 | AGTR1 (0.55) | AGTR1AGTAGTR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8602163 | 0.71 | AGT (0.41) | AGTR1AGTAGTR2 | |
| SCHEMBL9589082 | 0.71 | AGTR1 (0.52) | AGTR1AGTAGTR2 | |
| SCHEMBL9542915 | 0.71 | AGT (0.46) | AGTR1AGTAGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846991-A | Pyrazole derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-08 | — | — | US | disclosed |