Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS4 | P49798 | 2/20 | 0.58 |
| ▸ | RGS8 | P57771 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119500 | 0.81 | PRMT6 (0.46) | RGS4RGS8KMT2AALDH1A1MAPT | |
| SCHEMBL8528345 | 0.81 | RGS4 (0.43) | RGS4RGS8KMT2AL3MBTL1MAPT | |
| SCHEMBL13517224 | 0.80 | RGS4 (0.85) | RGS4RGS8 | |
| SCHEMBL8126612 | 0.77 | FEN1 (0.52) | ALDH1A1L3MBTL1MAPTERCC5FEN1 | |
| SCHEMBL13517577 | 0.75 | RGS4 (0.87) | RGS4RGS8 | |
| SCHEMBL8126895 | 0.75 | RGS4 (0.46) | RGS4RGS8ALDH1A1HPGD | |
| SCHEMBL24327517 | 0.74 | RGS4 (0.57) | RGS4RGS8MEN1KMT2AALDH1A1 | |
| SCHEMBL13517438 | 0.74 | RGS4 (1.00) | RGS4RGS8 | |
| SCHEMBL4211691 | 0.73 | MAPT (0.54) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL14611520 | 0.72 | MAPT (0.57) | MEN1KMT2AALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807875-A | OBESITY THERAPY | DR. KARL THOMAE GMBH (DE) | 1998-09-15 | — | — | US | disclosed |