Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS4 | P49798 | 5/20 | 0.43 |
| ▸ | RGS8 | P57771 | 5/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529611 | 0.81 | RGS4 (0.58) | RGS4RGS8MAPTKMT2AHPGD | |
| SCHEMBL8119500 | 0.81 | PRMT6 (0.46) | RGS4RGS8MAPK8MAPK9PGR | |
| SCHEMBL8126612 | 0.77 | FEN1 (0.52) | MAPTL3MBTL1 | |
| SCHEMBL8126895 | 0.75 | RGS4 (0.46) | RGS4RGS8MAPK8MAPK9PGR | |
| SCHEMBL11131835 | 0.70 | NPC1 (0.43) | MAPTCYP3A4HPGD | |
| SCHEMBL8985073 | 0.68 | GSK3B (0.67) | RGS4RGS8MAPTGSK3AGSK3B | |
| SCHEMBL9271953 | 0.67 | PGR (0.50) | MAPK8PGRMAPTGSK3AGSK3B | |
| SCHEMBL393865 | 0.67 | MAOA (0.56) | HPGD | |
| SCHEMBL1287433 | 0.67 | CALM1 (0.57) | — | |
| SCHEMBL8526739 | 0.65 | CNR1 (0.61) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807875-A | OBESITY THERAPY | DR. KARL THOMAE GMBH (DE) | 1998-09-15 | — | — | US | disclosed |