Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930648 | 0.92 | TSHR (0.36) | TSHRALDH1A1CYP4F2CYP4A11THRB | |
| SCHEMBL5076033 | 0.90 | ATM (0.47) | ATMTSHRALDH1A1MAPTHCAR2 | |
| SCHEMBL11516812 | 0.88 | MAPT (0.36) | ATMTSHRCYP3A4ALDH1A1CYP4F2 | |
| SCHEMBL8504051 | 0.87 | ATM (0.40) | ATMTSHRCYP3A4ALDH1A1CYP4F2 | |
| SCHEMBL5545986 | 0.85 | ALDH1A1 (0.32) | TSHRALDH1A1CYP4F2CYP4A11THRB | |
| SCHEMBL8504674 | 0.85 | NAAA (0.44) | ATMTSHRCYP3A4ALDH1A1HCAR2 | |
| SCHEMBL6923591 | 0.84 | DGKA (0.37) | ATMALDH1A1CYP4F2CYP4A11MAPT | |
| SCHEMBL11515685 | 0.83 | MEN1 (0.42) | ATMTSHRCYP4F2CYP4A11MAPT | |
| SCHEMBL8505385 | 0.83 | HCAR2 (0.38) | ATMTSHRALDH1A1HCAR2 | |
| SCHEMBL8679165 | 0.82 | TSHR (0.48) | ATMTSHRCYP3A4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760149-A | POLYMERIZATION INITIATORS, CURING AGENTS | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1998-06-02 | — | — | US | disclosed |