Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529945 | 1.00 | HSD11B1 (0.35) | HSD11B1RORCOPRM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8531175 | 0.87 | ALDH1A1 (0.39) | HSD11B1OPRM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8531171 | 0.87 | ALDH1A1 (0.39) | HSD11B1OPRM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8532213 | 0.82 | SLC6A4 (0.43) | KMT2A | |
| SCHEMBL8532204 | 0.82 | KMT2A (0.41) | SMN1; SMN2ALDH1A1MAPTMEN1NPC1 | |
| SCHEMBL8532211 | 0.82 | SLC6A4 (0.43) | KMT2A | |
| SCHEMBL8530705 | 0.82 | PDE2A (0.41) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8530709 | 0.82 | PDE2A (0.41) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8532199 | 0.82 | KMT2A (0.41) | SMN1; SMN2ALDH1A1MAPTMEN1NPC1 | |
| SCHEMBL8535754 | 0.80 | HDAC3 (0.37) | SMN1; SMN2ALDH1A1MAPTNPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763700-A | INSECTICIDES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |
| EP-0660815-B1 | PESTICIDAL FLUOROOLEFINS | BRITISH TECH GROUP (GB) | 1997-04-16 | — | — | EP | disclosed |
| EP-0660815-A1 | PESTICIDAL FLUOROOLEFINS. | BRITISH TECNOLOGY GROUP PLC (GB) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994006741-A1 | PESTICIDAL FLUOROOLEFINS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |