Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.41 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.41 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532204 | 1.00 | KMT2A (0.41) | KMT2ATET3FBXL19CXXC5TET1 | |
| SCHEMBL8529941 | 0.82 | HSD11B1 (0.35) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8529945 | 0.82 | HSD11B1 (0.35) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8532211 | 0.82 | SLC6A4 (0.43) | KMT2ASLC6A2SLC6A4SLC6A3PIM1 | |
| SCHEMBL8532213 | 0.82 | SLC6A4 (0.43) | KMT2ASLC6A2SLC6A4SLC6A3PIM1 | |
| SCHEMBL8530705 | 0.82 | PDE2A (0.41) | KMT2ALMNAPOLBMEN1ALDH1A1 | |
| SCHEMBL8530709 | 0.82 | PDE2A (0.41) | KMT2ALMNAPOLBMEN1ALDH1A1 | |
| SCHEMBL8531175 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8531171 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8531549 | 0.78 | NQO1 (0.41) | KMT2ATET3FBXL19CXXC5TET1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763700-A | INSECTICIDES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |
| EP-0660815-B1 | PESTICIDAL FLUOROOLEFINS | BRITISH TECH GROUP (GB) | 1997-04-16 | — | — | EP | disclosed |
| WO-1994006741-A1 | PESTICIDAL FLUOROOLEFINS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |