Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.35 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2804787 | 0.89 | CYP1A2 (0.38) | ALDH1A1PKMENPEPKMT2AATM | |
| SCHEMBL14674752 | 0.79 | ALDH1A1 (0.50) | ALDH1A1PKMENPEPGSTK1LMNA | |
| SCHEMBL27165392 | 0.75 | KMT2A (0.34) | ALDH1A1PKMENPEPGSTK1KMT2A | |
| SCHEMBL27500201 | 0.75 | ALDH1A1 (0.33) | ALDH1A1PKMENPEPGSTK1LMNA | |
| SCHEMBL30773222 | 0.74 | ALDH1A1 (0.49) | ALDH1A1PKMENPEPGSTK1LMNA | |
| SCHEMBL17821007 | 0.72 | ALDH1A1 (0.47) | ALDH1A1PKMGSTK1LMNATSHR | |
| SCHEMBL4310967 | 0.72 | GSTK1 (0.37) | ENPEPGSTK1LMNAKMT2ATSHR | |
| SCHEMBL846234 | 0.72 | ALDH1A1 (0.47) | ALDH1A1PKMGSTK1LMNATSHR | |
| SCHEMBL1251745 | 0.72 | ALDH1A1 (0.41) | ALDH1A1PKMKMT2AATMTSHR | |
| SCHEMBL826505 | 0.71 | LMNA (0.39) | ALDH1A1GSTK1LMNAKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869448-A | INHIBIT BINDING BETWEEN VLA-4 RECEPTOR AND FIBRONECTIN CS-1 PEPTIDES; TREATING IMMUNOINFLAMMATORY CONDITIONS | CYTEL CORPORATION (US) | 1999-02-09 | — | — | US | disclosed |
| US-5811391-A | INHIBITS BINDING BETWEEN THE VLA-4 RECEPTOR EXPRESSED ON INFLAMMATORY LEUKOCYTES AND A FIBRONECTIN; ANTIINFLAMMATORY AND-ARTHRITIC AGENTS; ASTHMA; OLIGOPEPTIDES | CYTEL CORPORATION (US) | 1998-09-22 | — | — | US | disclosed |