SCHEMBL8530333

SCHEMBL8530333

CCOC(=O)C(CC(C)C)C[PH](=O)COS(C)(=O)=O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8530713 0.80 KMT2A (0.39) HSD17B10
SCHEMBL8528855 0.79 HSD17B10 (0.35) HSD17B10
SCHEMBL31516111 0.75 HSD17B10 (0.36) HSD17B10
SCHEMBL9067420 0.75 SMN1; SMN2 (0.42) HSD17B10
SCHEMBL7047118 0.72 HSD17B10 (0.35) HSD17B10
SCHEMBL7046980 0.69 HSD17B10 (0.39) HSD17B10
SCHEMBL17617124 0.69 CPA1 (0.44) HSD17B10
SCHEMBL13555039 0.69 CPA1 (0.44) HSD17B10
SCHEMBL13541257 0.69 CPA1 (0.44) HSD17B10
SCHEMBL8763176 0.67 HSD17B10 (0.42) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5773428-A BONE DISORDERS SYNTEX (U.S.A.) INC. (US) 1998-06-30 US disclosed
EP-0807114-A1 BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS SYNTEX (U.S.A.) INC. (US) 1997-11-19 EP disclosed