Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067733 | 0.87 | CAPN1 (0.44) | HSD17B10NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL9067052 | 0.81 | GRIK1 (0.39) | NPC1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8528855 | 0.73 | HSD17B10 (0.35) | HSD17B10NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL7049694 | 0.72 | HSD17B10 (0.50) | HSD17B10NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL14874554 | 0.71 | HSD17B10 (0.56) | HSD17B10NPC1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8345051 | 0.71 | HSD17B10 (0.56) | HSD17B10NPC1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8530427 | 0.71 | ALDH1A1 (0.39) | HSD17B10NPC1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL9067050 | 0.71 | CYP3A4 (0.42) | NPC1KMT2AALDH1A1HPGDRAB9A | |
| SCHEMBL7049701 | 0.71 | ALDH1A1 (0.36) | HSD17B10NPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL31516111 | 0.70 | HSD17B10 (0.36) | HSD17B10NPC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726903-B1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX INC (US) | 1997-07-16 | — | — | EP | disclosed |