Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PPID | Q08752 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31516111 | 0.82 | HSD17B10 (0.36) | HSD17B10MEN1NPC1KMT2ACPA1 | |
| SCHEMBL9067738 | 0.81 | HDAC7 (0.38) | HSD17B10MEN1NPC1KMT2ACPB2 | |
| SCHEMBL7047118 | 0.79 | HSD17B10 (0.35) | HSD17B10MEN1NPC1KMT2ACPA1 | |
| SCHEMBL8530333 | 0.79 | HSD17B10 (0.32) | HSD17B10 | |
| SCHEMBL13541257 | 0.75 | CPA1 (0.44) | HSD17B10MEN1NPC1KMT2ACPA1 | |
| SCHEMBL13555039 | 0.75 | CPA1 (0.44) | HSD17B10MEN1NPC1KMT2ACPA1 | |
| SCHEMBL17617124 | 0.75 | CPA1 (0.44) | HSD17B10MEN1NPC1KMT2ACPA1 | |
| SCHEMBL8763176 | 0.73 | HSD17B10 (0.42) | HSD17B10MEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL9067255 | 0.72 | ALDH1A1 (0.36) | KMT2AALDH1A1 | |
| SCHEMBL30295340 | 0.72 | ALDH1A1 (0.41) | HSD17B10MEN1NPC1KMT2ACPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773428-A | BONE DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0807114-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1997-11-19 | — | — | EP | disclosed |
| EP-0726903-B1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX INC (US) | 1997-07-16 | — | — | EP | disclosed |