Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FGF2 | P09038 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461702 | 0.90 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTTSHRALDH1A1 | |
| SCHEMBL23566103 | 0.69 | ALDH1A1 (0.38) | SMN1; SMN2HPGDHTTTSHRALDH1A1 | |
| SCHEMBL14200373 | 0.68 | POLB (0.38) | SMN1; SMN2HPGDHTTALDH1A1MEN1 | |
| SCHEMBL10495316 | 0.66 | SMN1; SMN2 (0.41) | SMN1; SMN2HPGDHTTTSHRALDH1A1 | |
| SCHEMBL3143318 | 0.66 | — | — | |
| SCHEMBL57076 | 0.64 | ALDH1A1 (0.54) | SMN1; SMN2HPGDHTTALDH1A1MEN1 | |
| SCHEMBL6261105 | 0.64 | POLB (0.35) | HTTALDH1A1MEN1KMT2AFAAH | |
| SCHEMBL8863095 | 0.63 | POLB (0.43) | SMN1; SMN2HPGDHTTALDH1A1MEN1 | |
| SCHEMBL9724425 | 0.63 | SMN1; SMN2 (0.35) | SMN1; SMN2HPGDHTTTSHRALDH1A1 | |
| SCHEMBL24287571 | 0.63 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDHTTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994312-A | Peptidyl compounds | DARWIN DISCOVERY, LTD. (GB) | 1999-11-30 | — | — | US | disclosed |