Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367287 | 0.89 | TP53 (0.56) | TP53TDP1NR1I2ALDH1A1CYP3A4 | |
| SCHEMBL10730497 | 0.85 | TP53 (0.43) | TP53TDP1NR1I2ALDH1A1CYP3A4 | |
| SCHEMBL10733657 | 0.84 | TP53 (0.45) | TP53TDP1NR1I2ALDH1A1CYP3A4 | |
| SCHEMBL8433228 | 0.84 | TP53 (0.59) | TP53TDP1NR1I2ALDH1A1CYP3A4 | |
| SCHEMBL10732595 | 0.82 | TP53 (0.42) | TP53TDP1NR1I2ALDH1A1CYP3A4 | |
| SCHEMBL11101707 | 0.81 | TP53 (0.55) | TP53TDP1NR1I2ALDH1A1CYP3A4 | |
| SCHEMBL10732053 | 0.80 | TP53 (0.45) | TP53TDP1NR1I2ALDH1A1CYP3A4 | |
| SCHEMBL10732674 | 0.79 | TP53 (0.44) | TP53TDP1NR1I2ALDH1A1CYP3A4 | |
| Metazachlor SCHEMBL4896537 | 0.79 | TP53 (0.48) | TP53TDP1NR1I2ALDH1A1CYP3A4 | |
| SCHEMBL8460980 | 0.79 | TP53 (0.43) | TP53TDP1NR1I2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710100-A | ANTIDOTES WITH HERBICIDES FOR CROPS SUCH AS CORN | MONSANTO COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| US-5321000-A | Benzhydryl compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1994-06-14 | — | — | US | disclosed |
| US-5256626-A | Herbicidal compositions safened by 5-heterocyclic-substituted oxazolidine dihaloacetamides compounds | MONSANTO COMPANY (US) | 1993-10-26 | — | — | US | disclosed |
| US-5256625-A | Imidazolinone derivatives | MONSANTO COMPANY (US) | 1993-10-26 | — | — | US | disclosed |
| US-5256630-A | Safening mixtures of sulfonylurea and acetanilide herbicides | MONSANTO COMPANY (US) | 1993-10-26 | — | — | US | disclosed |
| EP-0230871-B1 | HALOACYL 1-SUBSTITUTED-1,2,3,4-TETRAHYDROISOQUINOLINES AS HERBICIDE ANTIDOTES | Monsanto Company (US) | 1993-09-22 | — | — | EP | disclosed |
| US-5225570-A | Plant safening agents for crops treated with herbicides | MONSANTO COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| US-5162537-A | To safen acetamide herbicids used to control grassy and broadleaf weeds in rice, sorghum and wheat | MONSANTO COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0304409-B1 | 5-HETEROCYCLIC-SUBSTITUTED OXAZOLIDINE HALOACETAMIDES | MONSANTO CO (US) | 1992-10-28 | — | — | EP | disclosed |
| EP-0436483-A2 | Safening imidazolinone herbicides | MONSANTO COMPANY (US) | 1991-07-10 | — | — | EP | disclosed |
| EP-0436484-A2 | Safening mixtures of sulfonylurea and acetanilide herbicides | MONSANTO COMPANY (US) | 1991-07-10 | — | — | EP | disclosed |
| US-4964893-A | REDUCING INJURY TO A CROP PLANT | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4859232-A | Substituted-aryl cyclopropanecarbonitriles and derivatives thereof as herbicide antidotes | MONSANTO COMPANY (US) | 1989-08-22 | — | — | US | disclosed |
| US-4846880-A | 2-(Dichloroacetyl)-3-substituted-1,2,3,4-tetrahydroisoquinolines as herbicide antidotes | MONSANTO COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| US-4818270-A | CROPS PLANT SAFENING AGENT | MONSANTO COMPANY (US) | 1989-04-04 | — | — | US | disclosed |
| US-4755218-A | Reducing acetochlor injury to corn by applying with antidote | MONSANTO COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| EP-0230871-A2 | Haloacyl 1-substituted-1,2,3,4-tetrahydroisoquinolines as herbicide antidotes | Monsanto Company (US) | 1987-08-05 | — | — | EP | disclosed |