Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367287 | 0.87 | TP53 (0.56) | TP53ALDH1A1LMNATHRBTDP1 | |
| SCHEMBL10753074 | 0.85 | ALDH1A1 (0.41) | TP53ALDH1A1TDP1NR1I2CYP3A4 | |
| SCHEMBL8433228 | 0.83 | TP53 (0.59) | TP53ALDH1A1LMNATHRBTDP1 | |
| SCHEMBL10344940 | 0.82 | TSHR (0.39) | LMNATHRBMEN1KMT2ATSHR | |
| SCHEMBL10900110 | 0.81 | TSHR (0.38) | LMNATHRBMEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL10900071 | 0.81 | TSHR (0.38) | LMNATHRBMEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL10896165 | 0.80 | TSHR (0.37) | LMNATHRBMEN1KMT2ATSHR | |
| Metazachlor SCHEMBL4896537 | 0.79 | TP53 (0.48) | TP53ALDH1A1THRBTDP1NR1I2 | |
| Metazachlor SCHEMBL55016 | 0.79 | TP53 (0.48) | TP53ALDH1A1THRBTDP1NR1I2 | |
| SCHEMBL8530433 | 0.79 | TP53 (0.44) | TP53ALDH1A1LMNATHRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990044-A | Selective herbicides based on aryl uracils | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-23 | — | — | US | claimed |