SCHEMBL8530450

SCHEMBL8530450

COC(=NO)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
GAA P10253 5/20 0.44
RAB9A P51151 2/20 0.40
HPGD P15428 3/20 0.39
ALDH1A1 P00352 2/20 0.39
SRC P12931 1/20 0.39
GFER P55789 1/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
CYP2C19 P33261 1/20 0.39
MAPT P10636 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
HTT P42858 2/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8530447 1.00 TSHR (0.48) TSHRGAARAB9AHPGDALDH1A1
SCHEMBL27532146 0.88 TSHR (0.39) TSHRGAARAB9AHPGDALDH1A1
SCHEMBL10268873 0.81 TSHR (0.48) TSHRGAARAB9AHPGDALDH1A1
SCHEMBL26741951 0.81 TSHR (0.48) TSHRGAARAB9AHPGDALDH1A1
SCHEMBL674618 0.80 GAA (0.41) TSHRGAAHPGDALDH1A1GFER
SCHEMBL10362382 0.79 CA1 (0.50) TSHRGAAHPGDALDH1A1GFER
SCHEMBL12151890 0.79 TSHR (0.46) TSHRGAARAB9AHPGDALDH1A1
SCHEMBL13962578 0.79 TSHR (0.46) TSHRGAARAB9AALDH1A1SRC
SCHEMBL27812844 0.79 TSHR (0.46) TSHRGAARAB9AHPGDALDH1A1
SCHEMBL14122944 0.79 TSHR (0.46) TSHRGAARAB9AHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118754134-A Method for preparing high-purity quartz sand by using feldspar granite pegmatite 合肥万泉非金属矿科技有限公司 2024-10-11 CN claimed
CN-118754134-A Method for preparing high-purity quartz sand by using feldspar granite pegmatite 合肥万泉非金属矿科技有限公司 2024-10-11 CN disclosed
US-20240122179-A1 AUXINIC HERBICIDES AND METHODS OF USE THEREOF CORTEVA AGRISCIENCE LLC (US) 2024-04-18 US disclosed
WO-2022170075-A1 AUXINIC HERBICIDES AND METHODS OF USE THEREOF CORTEVA AGRISCIENCE LLC (US) 2022-08-11 WO disclosed
CN-111471559-A Method for simultaneously preparing perilla brandy and perilla fermented beverage 通化师范学院 2020-07-31 CN disclosed
CN-1190434-C Novel heterocyclic compounds process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases REDDY RESEARCH FOUNDATION (IN) 2005-02-23 CN disclosed
CN-1119344-C Heterocyclic substed. pyrrolidine amide derivs. AVENTIS PHARMA INC (US) 2003-08-27 CN disclosed
CN-1098259-C Novel carboxy-substituted cyclic carboxamide derivatives AVENTIS PHARMA INC (US) 2003-01-08 CN disclosed
CN-1098264-C Substituted 4- (1H-benzimidazol-2-yl-amino) piperidines for the treatment of allergic diseases AVENTIS PHARMA INC (US) 2003-01-08 CN disclosed
CN-1080262-C Novel substituted 4-(1H-benzimidazol-2-YL) [1,4] diazepanes useful for the treatment of allergic diseases HOECHST MARION ROUSSEL INC (US) 2002-03-06 CN disclosed
US-5631253-A FUNGICIDES, INSECTICIDES AND MITICIDES USING METHYLOXIME PHENYLPROPENOIC ACID ZENECA LIMITED (GB) 1997-05-20 US disclosed
US-5432197-A Insecticidal, miticidal ZENECA LIMITED (GB) 1995-07-11 US disclosed
US-5371084-A Insecticides and miticides ZENECA LIMITED (GB) 1994-12-06 US disclosed
CN-1024005-C Fungicidal agents ICI PLC (GB) 1994-03-16 CN disclosed
EP-0506149-A2 Fungicides ZENECA LIMITED (GB) 1992-09-30 EP disclosed
US-5055471-A FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-10-08 US disclosed
CN-1042900-A Mycocide ICI PLC (GB) 1990-06-13 CN disclosed
EP-0370629-A1 Fungicides ZENECA LIMITED (GB) 1990-05-30 EP disclosed
US-4404384-A HYPOTENSIVE, ANTISPASMODIC, CHOLERETIC AGENTS; ANTICONUULSANTS; ANTIPYRETICS; ANTHELMINTICS; FUNGICIDWS HOECHST AKTIENGESELLSCHAFT (DE) 1983-09-13 US disclosed
US-4150043-A 0-(2,3-Epoxypropyl)-hydroximic acid esters HOECHST AKTIENGESELLSCHAFT (DE) 1979-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240122179-A1 AUXINIC HERBICIDES AND METHODS OF USE THEREOF DDT, HACL2, ALAD TSHR 817/4885GAA 700/4885RAB9A 2884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.