Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 9/20 | 0.42 |
| ▸ | SYK | P43405 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543452 | 0.90 | LOXL2 (0.44) | LOXL2SYKMEN1KMT2ALOX | |
| SCHEMBL8579703 | 0.90 | LOXL2 (0.44) | LOXL2SYKMEN1KMT2AALDH1A1 | |
| SCHEMBL21128589 | 0.83 | LOXL2 (0.43) | LOXL2SYKLOX | |
| SCHEMBL8546451 | 0.83 | LOXL2 (0.45) | LOXL2SYKLOX | |
| SCHEMBL8531463 | 0.82 | LOXL2 (0.41) | LOXL2LOXUTS2R | |
| SCHEMBL8531616 | 0.82 | LOXL2 (0.43) | LOXL2SYKMEN1KMT2ALOX | |
| SCHEMBL15390231 | 0.80 | LOXL2 (0.44) | LOXL2SYKLOX | |
| SCHEMBL8541968 | 0.80 | LOXL2 (0.54) | LOXL2LOX | |
| SCHEMBL23473283 | 0.80 | LOXL2 (0.42) | LOXL2SYKLOX | |
| SCHEMBL29728676 | 0.79 | AXL (0.48) | LOXL2MEN1KMT2AALDH1A1LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068450-A1 | CYCLOBUTYL SUBSTITUTED PYRROLOPYRIDINE AND PYRROLOPYRIMIDINE DERIVATIVES AS JAK INHIBITORS | INCYTE CORPORATION (US) | 2012-05-24 | — | — | WO | disclosed |