Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 19/20 | 0.74 |
| ▸ | GLA | P06280 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31219369 | 0.91 | GLA (0.74) | APPGLAGAAKDM4ENPC1 | |
| SCHEMBL13290891 | 0.91 | GLA (0.74) | APPGLAGAAKDM4ENPC1 | |
| SCHEMBL1986755 | 0.88 | MAPT (0.69) | APPGLAGAAKDM4ENPC1 | |
| SCHEMBL13806297 | 0.85 | APP (0.84) | APPGLAGAAKDM4ENPC1 | |
| SCHEMBL13806294 | 0.83 | APP (0.85) | APPGLAGAAKDM4ENPC1 | |
| SCHEMBL2628259 | 0.82 | MAPT (0.86) | APPGLAGAAKDM4ENPC1 | |
| SCHEMBL1995933 | 0.82 | MAPT (1.00) | APPGLAGAAKDM4ENPC1 | |
| SCHEMBL12509547 | 0.82 | APP (0.69) | APPGLAGAAKDM4ENPC1 | |
| SCHEMBL6854930 | 0.81 | MAPT (0.96) | APPGLAGAAKDM4ENPC1 | |
| SCHEMBL1727124 | 0.81 | APP (1.00) | APPGLAGAAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895313-B2 | Ligands for aggregated tau molecules | WISTA LABORATORIES LTD. (SG) | 2014-11-25 | — | — | US | disclosed |
| US-8895313-B2 | Ligands for aggregated tau molecules | WISTA LABORATORIES LTD. (SG) | 2014-11-25 | — | — | US | disclosed |
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | WISTA LABORATORIES LTD. | 2011-07-14 | — | — | US | disclosed |
| WO-2010034982-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | WISTA LABORATORIES LTD. (SG) | 2010-04-01 | — | — | WO | disclosed |
| EP-0581245-B1 | Water-insoluble azo colouring agents | CLARIANT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| US-5428136-A | Water-insoluble azo colorants having two azo groups and a 1,4-bis (acetoacetylamino) benzene coupling component | HOECHST AG (DE) | 1995-06-27 | — | — | US | disclosed |
| EP-0581245-A1 | Water-insoluble azo colouring agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | MAPT, PRNP, MAP4 | APP 17/4885GLA 1532/4885GAA 1252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.