Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530653 | 1.00 | CASP3 (0.47) | CASP3SENP8SENP7SENP6THRB | |
| SCHEMBL8528529 | 0.99 | CASP3 (0.48) | CASP3SENP8SENP7SENP6THRB | |
| SCHEMBL8528527 | 0.99 | CASP3 (0.48) | CASP3SENP8SENP7SENP6THRB | |
| SCHEMBL8530861 | 0.94 | LMNA (0.47) | CASP3SENP8SENP7SENP6THRB | |
| SCHEMBL8530864 | 0.94 | LMNA (0.47) | CASP3SENP8SENP7SENP6THRB | |
| SCHEMBL8528505 | 0.89 | ESR1 (0.52) | THRBLMNAALDH1A1TP53CYP3A4 | |
| SCHEMBL8532498 | 0.89 | ESR1 (0.52) | THRBLMNAALDH1A1TP53CYP3A4 | |
| SCHEMBL8531344 | 0.89 | ESR1 (0.52) | THRBLMNAALDH1A1TP53CYP3A4 | |
| SCHEMBL8531342 | 0.89 | ESR1 (0.52) | THRBLMNAALDH1A1TP53CYP3A4 | |
| SCHEMBL8527722 | 0.89 | ESR1 (0.52) | THRBLMNAALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733610-B1 | Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device | CHISSO CORP (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5635108-A | A HEXYNEDIENE DERIVATIVE | CHISSO CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0733610-A1 | Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device | Chisso Corporation (JP) | 1996-09-25 | — | — | EP | disclosed |