Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530861 | 1.00 | LMNA (0.47) | LMNAALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL8528529 | 0.95 | CASP3 (0.48) | LMNAALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL8528527 | 0.95 | CASP3 (0.48) | LMNAALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL8530653 | 0.94 | CASP3 (0.47) | LMNAALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL8530652 | 0.94 | CASP3 (0.47) | LMNAALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL8531435 | 0.91 | CYP3A4 (0.50) | LMNAALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL8531433 | 0.91 | CYP3A4 (0.50) | LMNAALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL13996325 | 0.89 | AHR (0.57) | LMNAALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL8528493 | 0.89 | SPHK1 (0.47) | LMNAALDH1A1TP53CYP3A4KDM4E | |
| SCHEMBL8528495 | 0.89 | SPHK1 (0.47) | LMNAALDH1A1TP53CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733610-B1 | Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device | CHISSO CORP (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5635108-A | A HEXYNEDIENE DERIVATIVE | CHISSO CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0733610-A1 | Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device | Chisso Corporation (JP) | 1996-09-25 | — | — | EP | disclosed |