Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530249 | 0.80 | HTR2A (0.37) | KDM1AHTR2AHTR2CHTR2BKDM4E | |
| SCHEMBL6227686 | 0.78 | SLC18A3 (0.38) | POLBHTR2BKDM4EHPGDNPC1 | |
| SCHEMBL472003 | 0.78 | SLC18A3 (0.38) | POLBHTR2BKDM4EHPGDNPC1 | |
| SCHEMBL8531187 | 0.75 | ABCC9 (0.34) | HPGDTSHR | |
| SCHEMBL2527089 | 0.72 | CHRNB2 (0.53) | KDM1APOLBMEN1KMT2ADRD2 | |
| SCHEMBL29086568 | 0.72 | CHRNB2 (0.53) | KDM1APOLBMEN1KMT2ADRD2 | |
| SCHEMBL29884098 | 0.72 | CHRNB2 (0.53) | KDM1APOLBMEN1KMT2ADRD2 | |
| SCHEMBL29964556 | 0.72 | CHRNB2 (0.53) | KDM1APOLBMEN1KMT2ADRD2 | |
| Hydrochloric Acid SCHEMBL22498444 | 0.71 | CHRNB2 (0.51) | KDM1APOLBMEN1KMT2AHTR2A | |
| Hydrochloric Acid SCHEMBL3725483 | 0.71 | CHRNB2 (0.51) | KDM1APOLBMEN1KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843966-A | Piperidine derivatives | GLAXO GROUP LIMITED (GB) | 1998-12-01 | — | — | US | disclosed |