Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532909 | 0.83 | LMNA (0.37) | NR4A2KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8530795 | 0.81 | MEN1 (0.39) | KMT2AMEN1NR4A2KDM4EALDH1A1 | |
| SCHEMBL8527729 | 0.77 | POLB (0.33) | KMT2AMEN1NR4A2KDM4EALDH1A1 | |
| SCHEMBL8527744 | 0.73 | NR4A2 (0.38) | KMT2AMEN1NR4A2SMN1; SMN2LMNA | |
| SCHEMBL788704 | 0.69 | GPR3 (0.37) | KMT2AMEN1NR4A2KDM4EALDH1A1 | |
| SCHEMBL8076272 | 0.68 | KMT2A (0.67) | KMT2AMEN1NR4A2KDM4EALDH1A1 | |
| SCHEMBL4603995 | 0.67 | NPSR1 (0.57) | SMN1; SMN2LMNAMAPTL3MBTL1 | |
| SCHEMBL315328 | 0.66 | GPR84 (0.55) | KMT2AMEN1NR4A2KDM4EALDH1A1 | |
| SCHEMBL8531617 | 0.65 | NR4A2 (0.37) | KMT2AMEN1NR4A2KDM4EALDH1A1 | |
| SCHEMBL4604311 | 0.65 | CNR2 (0.55) | KMT2AALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460679-B1 | Endothelin antagonistic peptide derivatives | BANYU PHARMA CO LTD (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5691315-A | CARDIOVASCULAR DISORDERS; VASODILATOR; BRONCHODILATOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5470833-A | Vasodilators, bronchodilators | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| US-5444152-A | Vasolidator or bronchodilator | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-22 | — | — | US | disclosed |
| EP-0460679-A2 | Endothelin antagonistic peptide derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-12-11 | — | — | EP | disclosed |